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NMR study of three heteroyohimbine derivatives from Rauwolfia serpentina : Stereochemical aspects of the two isomers of reserpiline hydrochloride
Author(s) -
De Bruyn André,
Zhang Weiguo,
Buděšinský Miloš
Publication year - 1989
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260271006
Subject(s) - chemistry , hydrochloride , coupling constant , carbon 13 nmr , stereochemistry , nuclear magnetic resonance spectroscopy , proton nmr , computational chemistry , organic chemistry , physics , particle physics
1 H NMR data for isoreserpiline and tetraphylline and 1 H and 13 C NMR data for reserpiline hydrochloride are presented. New insights into the 1 H NMR coupling constants of the heteroyohimibines provide an easy means of assigning their configuration and conformation, allowing the elucidation of the stereochemical features of the two isomers of reserpiline hydrochloride.