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2 H NMR study of the behaviour of water in a reversed micellar system. Hydrogen bond breaking and clathrate formation by an inhalation anaesthetic
Author(s) -
Yoshino Akihiro,
Yoshida Tadayoshi,
Takahashi Kensuke
Publication year - 1989
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260270409
Subject(s) - chemistry , deuterium , molecule , hydrogen bond , decane , clathrate hydrate , hydrogen , enflurane , dissociation (chemistry) , hydrate , organic chemistry , physics , quantum mechanics , halothane
The behaviour of water in the reversed micelles of the glycerol α‐monooleate (GMO)–decane‐ 2 H 2 O system was investigated by deuteron nuclear magnetic resonance. The chemical shifts (δ) and the spin–lattice relaxation times ( T 1 ) of heavy water were found to be dependent on temperature. The temperature dependence of the T 1 and δ values reveals that the structural change in heavy water induced by the inhalation anaesthetic enflurane is very different below and above ca . 300 K. Below ca . 300 K a cage of a water polyhedron builds up around an enflurane molecule. Above ca . 300 K there is no water polyhedron cage because of the cleavage of the hydrogen bonds in the polyhedron water, and some of the water molecules are tightly adsorbed on the enflurane molecules.