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1 H and 13 C resonance designation of antimycin A 1 by two‐dimensional NMR spectroscopy
Author(s) -
Abidi S. L.,
Adams B. R.
Publication year - 1987
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260251212
Subject(s) - homonuclear molecule , heteronuclear molecule , chemistry , nuclear magnetic resonance spectroscopy , resonance (particle physics) , nuclear magnetic resonance , antimycin a , two dimensional nuclear magnetic resonance spectroscopy , nmr spectra database , spectroscopy , spectral line , crystallography , stereochemistry , molecule , physics , atomic physics , organic chemistry , biochemistry , astronomy , electron transport chain , quantum mechanics
Complete 1 H and 13 C resonance assignments of antimycin A 1 were accomplished by two‐dimensional NMR techniques, viz. 1 H homonuclear COSY correlation, heteronuclear 13 C‐ 1 H chemical shift correlation and long‐range heteronuclear 13 C‐ 1 H COLOC correlation. Antimycin A 1 was found to consist of two isomeric components in a 2:1 ratio based on NMR spectroscopic evidence. The structure of the major component was newly assigned as the 8‐isopentanoic acid ester. The spectra of the minor component were consistent with the known structure of antimycin A 1 .