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Optimized detection of small spin–spin couplings in two‐dimensional chemical shift correlation experimentsCOSY and DEPT
Author(s) -
Batta Gy.,
Kövér Katalin E.
Publication year - 1987
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260250208
Subject(s) - dept , chemistry , spin (aerodynamics) , pulse sequence , two dimensional nuclear magnetic resonance spectroscopy , sensitivity (control systems) , analytical chemistry (journal) , nuclear magnetic resonance , physics , chromatography , stereochemistry , electronic engineering , thermodynamics , engineering
Two‐dimensional chemical shift correlation experiments (COSY and DEPT) may be applied to the detection of small spin‐spin couplings. To increase the sensitivity of these techniques, careful optimization of the experimental parameters is required. Equations applicable to AX spin systems are given for the optimal choice of delay periods in the pulse sequences. Practical applications have been demonstrated for oligosaccharide sequencing.