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Comparison of rate constants determined by two‐dimensional NMR spectroscopy with rate constants determined by other NMR techniques
Author(s) -
Baine Peter
Publication year - 1986
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260240407
Subject(s) - chemistry , reaction rate constant , nuclear magnetic resonance spectroscopy , spectroscopy , analytical chemistry (journal) , saturation (graph theory) , proton nmr , conformational isomerism , nuclear magnetic resonance , molecule , kinetics , organic chemistry , physics , mathematics , quantum mechanics , combinatorics
Rate constants for the interconversion of N ‐trifluoroacetyl‐ N ‐methylbenzylamine between its conformers were measured over a temperature range by two‐dimensional NMR spectroscopy. These rate constants were compared with those obtained by line shape analysis, saturation transfer and selective pulse transfer. The rate constants measured by the two‐dimensional method were, over the temperature range of the experiments, about 40% higher than those from line shape analysis. At lower temperatures, the agreement between the two‐dimensional data and the rate constants obtained by saturation transfer and selective pulse transfer studies were much closer. The two‐dimensional NMR method for measuring rate constants gives good agreement with rate constants obtained by other NMR methods, particularly in the slow rate region.