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Inconsistent Solvent Shifts Caused by benzene in the NMR spectra of N ‐alkyl(thio)phosphonothioamides
Author(s) -
Tashma Zeev
Publication year - 1985
Publication title -
magnetic resonance in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0749-1581
DOI - 10.1002/mrc.1260230502
Subject(s) - chemistry , thio , phosphonate , benzene , alkyl , moiety , solvent , proton nmr , chloroform , nmr spectra database , stereochemistry , medicinal chemistry , chemical shift , spectral line , organic chemistry , physics , astronomy
Replacement of chloroform by benzene as an NMR solvent for a series of (thio)phosphonothioamides results in an exceptionally wide range of shifts for the N CH proton signals, from an upfield shift of approximately 1 ppm to a downfield shift of about 0.1 ppm, depending on the phosphonate esterifying groups, the type of the N ‐alkyl moiety and whether it is a PO or a PS compound. The last factor is believed to operate indirectly by affecting the aggregation state of the compounds in benzene.