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High risk cohort study for psychiatric disorders in childhood: rationale, design, methods and preliminary results
Author(s) -
Salum Giovanni Abrahão,
Gadelha Ary,
Pan Pedro Mario,
Moriyama Tais Silveira,
GraeffMartins Ana Soledade,
Tamanaha Ana Carina,
Alvarenga Pedro,
Krieger Fernanda Valle,
FleitlichBilyk Bacy,
Jackowski Andrea,
Sato João Ricardo,
Brietzke Elisa,
Polanczyk Guilherme Vai,
Brentani Helena,
Mari Jair,
Do Rosário Maria Conceição,
Manfro Gisele Gus,
Bressan Rodrigo Affonseca,
Mercadante Marcos Tomanik,
Miguel Eurípedes Constantino,
Rohde Luis Augusto
Publication year - 2015
Publication title -
international journal of methods in psychiatric research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.275
H-Index - 73
eISSN - 1557-0657
pISSN - 1049-8931
DOI - 10.1002/mpr.1459
Subject(s) - inter rater reliability , psychopathology , child psychopathology , psychiatry , cohort , child and adolescent psychiatry , psychology , conduct disorder , clinical psychology , diagnostic classification of mental health and developmental disorders of infancy and early childhood , medicine , mental health , prevalence of mental disorders , developmental psychology , rating scale
The objective of this study is to present the rationale, methods, design and preliminary results from the High Risk Cohort Study for the Development of Childhood Psychiatric Disorders . We describe the sample selection and the components of each phases of the study, its instruments, tasks and procedures. Preliminary results are limited to the baseline phase and encompass: (i) the efficacy of the oversampling procedure used to increase the frequency of both child and family psychopathology; (ii) interrater reliability and (iii) the role of differential participation rate. A total of 9937 children from 57 schools participated in the screening procedures. From those 2512 (random =958; high risk =1554) were further evaluated with diagnostic instruments. The prevalence of any child mental disorder in the random strata and high‐risk strata was 19.9% and 29.7%. The oversampling procedure was successful in selecting a sample with higher family rates of any mental disorders according to diagnostic instruments. Interrater reliability (kappa) for the main diagnostic instrument range from 0.72 (hyperkinetic disorders) to 0.84 (emotional disorders). The screening instrument was successful in selecting a sub‐sample with “high risk” for developing mental disorders. This study may help advance the field of child psychiatry and ultimately provide useful clinical information. Copyright © 2014 John Wiley & Sons, Ltd.

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