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Advanced Treatment Planning
Author(s) -
Wedenberg Minna,
Beltran Chris,
Mairani Andrea,
Alber Markus
Publication year - 2018
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1002/mp.12943
Subject(s) - radiation treatment planning , plan (archaeology) , computer science , medical physics , dosimetry , relative biological effectiveness , systems engineering , physics , engineering , nuclear medicine , medicine , radiation therapy , nuclear physics , irradiation , radiology , archaeology , history
Treatment planning for protons and heavier ions is adapting technologies originally developed for photon dose optimization, but also has to meet its particular challenges. Since the quality of the applied dose is more sensitive to geometric uncertainties, treatment plan robust optimization has a much more prominent role in particle therapy. This has led to specific planning tools, approaches, and research into new formulations of the robust optimization problems. Tools for solution space navigation and automatic planning are also being adapted to particle therapy. These challenges become even greater when detailed models of relative biological effectiveness ( RBE ) are included into dose optimization, as is required for heavier ions.