Premium
Front Cover: 5‐Heptadecylresorcinol Protects against Atherosclerosis in Apolipoprotein E‐Deficient Mice by Modulating SIRT3 Signaling: The Possible Beneficial Effects of Whole Grain Consumption
Author(s) -
Hao Yiming,
Yang Zihui,
Li Qing,
Wang Ziyuan,
Liu Jie,
Wang Jing
Publication year - 2022
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.202270025
Subject(s) - sirt3 , umbilical vein , apolipoprotein b , endocrinology , medicine , biology , cholesterol , biochemistry , sirtuin , acetylation , in vitro , gene
Mol. Nutr. Food Res . 2022, 66 , 202101114 DOI: 10.1002/mnfr.202101114 As a biomarker for whole grain dietary intake, 5‐heptadecylresorcinol (AR‐C17) has been evidenced to alleviate atherosclerosis by improving endothelial cell mitochondrial function via the SIRT3 signaling pathway both in apolipoprotein E‐deficient mice and ox‐LDL‐treated human umbilical vein endothelial cells. This is reported by Jie Liu, Jing Wang, and co‐workers in article number 2101114.