Premium
Front Cover: A Systematic Review of Metabolic Alterations Underlying IgE‐Mediated Food Allergy in Children
Author(s) -
De Paepe Ellen,
Van Gijseghem Lynn,
De Spiegeleer Margot,
Cox Eric,
Vanhaecke Lynn
Publication year - 2021
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.202170062
Subject(s) - immunoglobulin e , allergy , front cover , immunology , biology , metabolomics , biochemistry , bioinformatics , antibody , cover (algebra) , mechanical engineering , engineering
Mol. Nutr. Food Res . 2021, 65 , 202100536 DOI: 10.1002/mnfr.202100536 IgE‐mediated food allergies (IgE‐FA) are considered a growing epidemic. Its pathogenic mechanisms remain however largely unknown. The authors performed a literature search followed by in‐depth pathway mapping of IgE‐FA in children, and revealed a shift in energy metabolism, next to aberrant metabolization of bile acids, lipids, nucleotides, fecal SCFAs and amino acids. As such, this work confirmed the unprecedented opportunities of metabolomics while offering a solid basis for future FA research. This is reported by Lynn Vanhaecke and co‐workers in article number 2100536.