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Front Cover: Altered Gut Microbiota is Involved in the Anti‐Hypertensive Effects of Vitamin C in Spontaneously Hypertensive Rat
Author(s) -
Li Ying,
Salih Ibrahim Rawya Mohamed,
Chi HongLi,
Xiao Tong,
Xia WenJie,
Li HongBao,
Kang YuMing
Publication year - 2021
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.202170015
Subject(s) - gut flora , blood pressure , vitamin , vitamin c , medicine , endocrinology , vitamin d and neurology , physiology , immunology
Mol. Nutr. Food Res . 2021, 65 , 2000885 DOI: 10.1002/mnfr.202000885 Hypertensive rats receiving daily oral Vitamin C intake showed reduction in their blood pressure. Analysis suggested improvements in the diversity and abundance of their gut microbiota, which contributed to restore the gut structure and function, and reduced the pro‐inflammatory cytokines in both gut and hypothalamic paraventricular nucleus. Together, Vitamin C influences the gut microbiota in achievement of its anti‐hypertensive effects. This is reported by Ying Li, Rawya Mohamed Salih Ibrahim, Hong‐Li Chi, Tong Xiao, Wen‐Jie Xia, Hong‐Bao Li, Yu‐Ming Kang in article 2000885.