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Front Cover: Improved Glucose Intolerance through a Distinct Mouse Olfactory Receptor 23‐Induced Signaling Pathway Mediating Glucose Uptake in Myotubes and Adipocytes
Author(s) -
Kang Wesuk,
Zhang Kelun,
Tong Tao,
Park Taesun
Publication year - 2020
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.202070052
Subject(s) - glucose uptake , medicine , endocrinology , receptor , myogenesis , glucose transporter , agonist , stimulation , biology , chemistry , microbiology and biotechnology , insulin , myocyte
Mol. Nutr. Food Res . 2020, 64 , 1901329 DOI: 10.1002/mnfr.201901329 This study evaluates the role of mouse olfactory receptor 23 (MOR23) in the regulation of glucose uptake in myotubes and adipocytes. MOR23 stimulation by the agonist (cedrene) results in increased glucose uptake, which is absent in MOR23‐depleted myotubes and adipocytes. These data show that MOR23 is a novel factor for the regulation of glucose uptake and has therapeutic potential for diabetes treatment. This is reported by Wesuk Kang, Kelun Zhang, Tao Tong, and Taesun Park in article 1901329.