Premium
Front Cover: Ellagic Acid and Its Microbial Metabolite Urolithin A Alleviate Diet‐Induced Insulin Resistance in Mice
Author(s) -
Yang Jieping,
Guo Yuanqiang,
Henning Susanne M.,
Chan Brenda,
Long Jianfeng,
Zhong Jin,
AcinPerez Rebeca,
Petcherski Anton,
Shirihai Orian,
Heber David,
Li Zhaoping
Publication year - 2020
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.202070043
Subject(s) - ellagic acid , metabolite , metabolism , insulin resistance , chemistry , biochemistry , insulin , biology , endocrinology , antioxidant , polyphenol
Mol. Nutr. Food Res . 2020, 64 , 2000091 DOI: 10.1002/mnfr.202000091 Large inter‐individual variation of microbial conversion of ellagic acid (EA) into urolithin A (UA) is known in humans. EA and UA intake result in differential metabolic benefits and mitochondrial dynamics in insulin resistant mice. These data suggest that individuals capable of UA production will experience the most benefits of EA intake in regards to glucose metabolism and mitochondrial health. This is reported by Jieping Yang, Yuanqiang Guo, Susanne M. Henning, Brenda Chan, Jianfeng Long, Jin Zhong, Rebeca Acin‐Perez, Anton Petcherski, Orian Shirihai, David Heber, Zhaoping Li in article 2000091.