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Front Cover: Targeting the NLRP3 Inflammasome in Neuroinflammation: Health Promoting Effects of Dietary Phytochemicals in Neurological Disorders
Author(s) -
Hung WeiLun,
Ho ChiTang,
Pan MinHsiung
Publication year - 2020
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.202070009
Subject(s) - inflammasome , neuroinflammation , neuroprotection , neurology , medicine , caspase 1 , neuroscience , pharmacology , immunology , biology , psychiatry , inflammation
Mol. Nutr. Food Res . 2020, 64 , 1900550 DOI: 10.1002/mnfr.201900550 Assembly of the NLRP3 inflammasome, consisting of ASC, NLRP3, and pro‐caspase‐1, promotes neuroinflammation in neurological disorders. In article 1900550, Wei‐Lun Hung, Chi‐Tang Ho, and Min‐Hsiung Pan summarize the pathogenic role of the NLRP3 inflammasome in neuroinflammation and highlight the current knowledge on the neuroprotective effects of phytochemicals for the treatment and prevention of neurological disorders through modulation of the NLRP3 inflammasome.