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Back cover: Endothelial Cells Deconjugate Resveratrol Metabolites to Free Resveratrol: A Possible Role in Tissue Factor Modulation
Author(s) -
FernándezCastillejo Sara,
Macià Alba,
Motilva MariaJosé,
Catalán Úrsula,
Solà Rosa
Publication year - 2019
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201970009
Subject(s) - resveratrol , antithrombotic , endothelium , chemistry , endothelial dysfunction , biochemistry , medicine
Mol. Nutr. Food Res. 2019, 63 , 1800715 DOI: 10.1002/mnfr.201800715 In article number 1800715 , Úrsula Catalán and co‐workers incubate resveratrol (RV) and its main metabolites (RVmet) with endothelial cells to test their antithrombotic activity and endothelial metabolism. RV modulated tissue factor and was conjugated to RVmet in the endothelium. The endothelium's capacity to deconjugate RVmet to free RV indicates that RVmet serve as an endothelial reservoir for RV regeneration contributing to the antithrombotic effects of RV.