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Front cover: α‐Cedrene, a Newly Identified Ligand of MOR23, Increases Skeletal Muscle Mass and Strength
Author(s) -
Tong Tao,
Kim Minji,
Park Taesun
Publication year - 2018
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201870077
Subject(s) - skeletal muscle , muscle hypertrophy , atrophy , muscle atrophy , endocrinology , medicine , ligand (biochemistry) , receptor , chemistry , microbiology and biotechnology , biology
Mol. Nutr. Food Res. 2018, 62 , 1800173 DOI: 10.1002/mnfr.201800173 Skeletal muscle atrophy is a common and debilitating condition that lacks an effective therapy. α‐Cedrene, a newly identified natural ligand of mouse olfactory receptor 23, induces skeletal muscle hypertrophy in chow‐fed mice and attenuates muscle atrophy in HFD‐fed mice. α‐Cedrene‐induced activation of the MOR23–cAMP–PKA–CREB pathway is a likely mechanism contributing to hypertrophic and antiatrophic effects of α‐cedrene. Further details can be found in article number 1800173 by Taesun Park and co‐workers.