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Vegan and Animal Meal Composition and Timing Influence Glucose and Lipid Related Postprandial Metabolic Profiles
Author(s) -
Draper Colleen Fogarty,
Tini Giulia,
Vassallo Irene,
Godin Jean Philippe,
Su MingMing,
Jia Wei,
Beaumont Maurice,
Moco Sofia,
Martin FrancoisPierre
Publication year - 2019
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201800568
Subject(s) - vegan diet , postprandial , glycemic , food science , meal , crossover study , biology , insulin , medicine , endocrinology , placebo , alternative medicine , pathology
Scope Flexitarian dieting is increasingly associated with health benefits. The study of postprandial metabolic response to vegan and animal diets is essential to decipher how specific diet components may mediate metabolic changes. Methods and results A randomized, crossover, controlled vegan versus animal diet challenge is conducted on 21 healthy participants. Postprandial metabolic measurements are conducted at seven timepoints. Area under the curve analysis of the vegan diet response demonstrates higher glucose (EE 0.35), insulin (EE 0.38), triglycerides (EE 0.72), and nine amino acids at breakfast (EE 4.72–209.32); and six lower health‐promoting fatty acids at lunch (EE −0.1035 to −0.13) ( p < 0.05). Conclusions Glycemic and lipid parameters vary irrespective of diet type, demonstrating that vegan and animal meals contain health‐promoting and suboptimal nutrient combinations. The vegan breakfast produces the same pattern of elevated branched chain amino acids, insulin, and glucose as the animal diet from the fasting results, reflecting the low protein load in the animal and the higher branched‐chain amino acid load of the vegan breakfast. Liberalization of the vegan menu to vegetarian and the animal menu to a Nordic‐based diet can result in optimal metabolic signatures for both flexitarian diet strategies in future research.