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Front cover: Hypoglycemic activity of the Baker's yeast β‐glucan in obese/type 2 diabetic mice and the underlying mechanism
Author(s) -
Cao Yan,
Zou Siwei,
Xu Hui,
Li Mengxia,
Tong Zan,
Xu Min,
Xu Xiaojuan
Publication year - 2016
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201670121
Subject(s) - akkermansia , front cover , gut flora , endocrinology , population , yeast , medicine , type 2 diabetes , inflammation , glucose homeostasis , glucan , diabetes mellitus , biology , chemistry , biochemistry , insulin resistance , cover (algebra) , mechanical engineering , environmental health , fermentation , engineering , lactobacillus
Mol. Nutr. Food Res . 2016, 60 , 2678–2690. DOI: 10.1002/mnfr.201600032 The yeast β‐glucan (BYGlc) orally given to diet‐induced obese/type 2 diabetic mice improves hepatic glucose‐lipid homeostasis. BYGlc decreases blood glucose through inhibiting intestine SGLT‐1 expression, and alters the gut microbiota by increasing Akkermansia population, which may be associated with reduced inflammation.