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Front cover: Glutamine promotes intestinal SIgA secretion through intestinal microbiota and IL‐13
Author(s) -
Wu Miaomiao,
Xiao Hao,
Liu Gang,
Chen Shuai,
Tan Bie,
Ren Wenkai,
Bazer Fuller W.,
Wu Guoyao,
Yin Yulong
Publication year - 2016
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201670071
Subject(s) - glutamine , secretion , front cover , immunoglobulin a , intestinal mucosa , biology , microbiology and biotechnology , chemistry , antibody , immunology , biochemistry , medicine , immunoglobulin g , amino acid , cover (algebra) , mechanical engineering , engineering
Mol. Nutr. Food Res . 2016, 60 , 1637–1648. DOI: 10.1002/mnfr.201600026 The mechanism of promoted intestinal secretory immunoglobulin A (SIgA) production by glutamine supplementation is investigated in a mouse model. It is found that glutamine influences the intestinal bacterial invasion and the activation of T cell‐dependent and T cell‐independent pathways, which leads to enhanced SIgA secretion.