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Is mealworm or shrimp allergy indicative for food allergy to insects?
Author(s) -
Broekman Henrike C. H. P.,
Knulst André C.,
Jong Govardus,
Gaspari Marco,
Hartog Jager Constance F.,
Houben Geert F.,
Verhoeckx Kitty C. M.
Publication year - 2017
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201601061
Subject(s) - mealworm , allergy , grasshopper , shrimp , biology , population , basophil activation , food allergy , zoology , immunology , ecology , medicine , immunoglobulin e , larva , environmental health , basophil , antibody
Scope The growing world population is a key driver for the exploration of sustainable protein sources to ensure food security. Mealworm and other insects are promising candidates. Previously we found that shrimp allergic patients are at risk for mealworm allergy, and that mealworm can induce a primary allergy [3][Broekman, H. C, 2016]. This study set out to investigate the allergenic potential of edible insects, suggested for human consumption by agencies such as WHO/FAO, in both the shrimp (potentially cross‐reactive) and primary mealworm allergic population. The following insects were studied: mealworm, house cricket, giant mealworm, lesser mealworm, African grasshopper, large wax moth, and black soldier fly. Methods and results Fifteen shrimp (mealworm sensitized or allergic) patients and four primary mealworm allergic subjects, who participated in previous studies, were included. All shrimp allergic patients were sensitized to multiple insects with similar response profiles for all insects tested. Primary mealworm allergic patients, showed IgE binding to proteins from only a few insects on immunoblot, although basophil activation test was positive for all tested insects. Conclusion Shrimp allergic patients are most likely at risk of food allergy to mealworm and other insects. Primary mealworm allergy does not mean subjects are likely to react to all insects.