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Distribution of serum transferrin, and its associations with metabolic disorders among Chinese: A nation‐wide, health and nutrition survey
Author(s) -
Zhao HongQiang,
Wu He,
Meng Ran,
Du Shufa,
Tao ShuJuan
Publication year - 2015
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201500038
Subject(s) - transferrin , medicine , obesity , waist , overweight , body mass index , diabetes mellitus , endocrinology , metabolic syndrome , anthropometry , national health and nutrition examination survey , carbohydrate deficient transferrin , population , physiology , biology , environmental health , biochemistry , alcohol , alcohol consumption
Scope This study examined the associations of serum transferrin and metabolic disorders among Chinese population. Methods and results This study is based on nation‐wide, population‐based China Health and Nutrition survey including 8564 men and women aged 18 years or older. Anthropometric and fasting blood glucose, insulin, lipids, and transferrin data were collected. Elevated transferrin concentrations associated with higher body mass index, waist circumference, lipids, insulin, glucose (all p < 0.0001). Serum transferrin concentrations increased gradually with increasing numbers of metabolic syndrome (MetS) components among men and women ( p = 0.0003). Elevated concentrations of transferrin were significantly related with higher risk of MetS ( p = 0.0006), obesity ( p = 0.0089), overweight ( p < 0.0001). No associations between transferrin concentrations and risk of diabetes and high blood pressure were observed in both men and women. Conclusion Elevated transferrin concentrations were positively associated with risk of MetS and obesity, but not with risk of diabetes among Chinese.