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Fiber consumption and all‐cause, cardiovascular, and cancer mortalities: A systematic review and meta‐analysis of cohort studies
Author(s) -
Liu Lihua,
Wang Shan,
Liu Jianchao
Publication year - 2015
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201400449
Subject(s) - medicine , meta analysis , hazard ratio , mortality rate , cause of death , cohort study , cancer , confidence interval , disease
The present meta‐analysis aimed to investigate fiber consumption and all‐cause mortality, and cause‐specific mortality. MEDLINE and web of science database were searched for cohort studies published from inception to August 2014. Studies were included if they provided a hazard ratio (HR) and corresponding 95% CI for mortality in relation to fiber consumption.We found that, compared with those who consumed lowest fiber, for individuals who ate highest fiber, mortality rate was lower by 23% (HR, 0.77; 95% CI, 0.72–0.81) for CVD, by 17% (HR, 0.83; 95% CI, 0.74–0.91) for cancer, by 23% (HR, 0.77; 95% CI, 0.73–0.81) for all‐cause mortality. For each 10 g/day increase in fiber intake, the pooled HR was estimated to be 0.89 (95% CI, 0.86–0.93) for all‐cause mortality, 0.80 (95% CI, 0.72–0.88) for CHD mortality, and 0.66 (95% CI, 0.40–0.92) for IHD mortality, 0.91 (95% CI, 0.88–0.94) for cancer. Dietary fiber and CVD mortality showed a strong dose–response relation. Apparently, fiber consumption is inversely associated with all‐cause mortality and CVD, IHD, cancer mortality.