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Extract of I rish potatoes ( S olanum tuberosum L.) decreases body weight gain and adiposity and improves glucose control in the mouse model of diet‐induced obesity
Author(s) -
Kubow Stan,
Hobson Luc,
Iskandar Michèle M.,
Sabally Kebba,
Donnelly Danielle J.,
Agellon Luis B.
Publication year - 2014
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.201400013
Subject(s) - leptin , ghrelin , resistin , endocrinology , medicine , obesity , weight gain , insulin , diabetes mellitus , chemistry , body weight , biology , food science , hormone , adipokine
Both sexes of mice were fed a high fat diet ( HFD ) for 10 weeks without and with polyphenolic‐rich potato extracts ( PRPE ) of cultivars Onaway and Russet Burbank. PRPE attenuated weight gain in male and female mice by as much as 63.2%, which was associated mostly with a reduction in adiposity. Mice receiving PRPE showed enhanced capacity for blood glucose clearance. Sex differences regarding the impact of HFD and PRPE on plasma levels of insulin, ghrelin, leptin, gastric inhibitory peptide, and resistin were noted. PRPE may serve as part of a preventative dietary strategy against the development of obesity and type 2 diabetes.