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S100B Protein concentration in milk‐formulas for preterm and term infants Correlation with industrial preparation procedures
Author(s) -
Nigro Francesco,
Gagliardi Luigi,
Ciotti Sabina,
Galvano Fabio,
Pietri Amedeo,
Tina Gabriella Lucia,
Cavallaro Daniela,
La Fauci Luca,
Iacopino Leonardo,
Bognanno Matteo,
Li Volti Giovanni,
Scacco Antonio,
Michetti Fabrizio,
Gazzolo Diego
Publication year - 2008
Publication title -
molecular nutrition and food research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.495
H-Index - 131
eISSN - 1613-4133
pISSN - 1613-4125
DOI - 10.1002/mnfr.200700312
Subject(s) - pasteurization , infant formula , cow milk , food science , skimmed milk , dairy industry , zoology , medicine , chemistry , biology
Human milk S100B protein possesses important neurotrophic properties. However, in some conditions human milk is substituted by milk formulas. The aims of the present study were: to assess S100B concentrations in milk formulas, to verify any differences in S100B levels between preterm and term infant formulas and to evaluate the impact of industrial preparation at predetermined phases on S100B content. Two different set of samples were tested: (i) commercial preterm (n = 36) and term (n = 36) infant milk formulas; ii) milk preterm (n = 10) and term infant (n = 10) formulas sampled at the following predetermined industrial preparation time points: skimmed cow milk (Time 0); after protein sources supplementation (Time 1); after pasteurization (Time 2); after spray‐drying (Time 3). Our results showed that S100B concentration in preterm formulas were higher than in term ones ( p < 0.01). In addition, S100B concentrations during industrial preparation showed a significant increase ( p < 0.001) at Time 1 followed by a slight decrease ( p > 0.05) at Time 2, whereas a significant ( p < 0.001) dip was observed at Time 3. In conclusion, S100B showed a sufficient thermostability to resist pasteurization but not spry‐drying. New feeding strategies in preterm and term infants are therefore warranted in order to preserve S100B protein during industrial preparation.