Premium
On the mathematical foundations of hyperthermia therapy
Author(s) -
Kremer Jüurgen,
Louis Alfred K.
Publication year - 1990
Publication title -
mathematical methods in the applied sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.719
H-Index - 65
eISSN - 1099-1476
pISSN - 0170-4214
DOI - 10.1002/mma.1670130603
Subject(s) - operator (biology) , antenna (radio) , microwave , parabolic antenna , homogeneous , mathematics , field (mathematics) , degree (music) , radiation , computer science , physics , optics , acoustics , pure mathematics , telecommunications , biochemistry , chemistry , repressor , combinatorics , transcription factor , gene
Hyperthermia is an aid to standard cancer therapy. The aim is to heat up a tumour region inside the patient's body with the help of microwave radiation. The microwayes are generated by some suitable antenna array. Here we investigate the control properties of such antenna configurations and determine their resolution capabilities. We will define the hyperthermia operator, which can produce every field of any antenna array up to any degree of accuracy. We shall see that this operator is compact and we are able to compute a singular system under general assumptions explicitly. This, together with a detailed knowledge of the decay of the singular values, constitutes the tools with which we treat the previously stated problems. We examine the propagation of microwave radiation in homogeneous media and then carry over the results obtained to the case of inhomogeneous media.