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Impact of advanced age on microvascular reconstruction of the lower facial third: An American College of Surgeons NSQIP study
Author(s) -
Torabi Sina J.,
Chouairi Fouad,
Dinis Jacob,
Alperovich Michael
Publication year - 2019
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.30455
Subject(s) - medicine , surgery , univariate analysis , population , perioperative , cohort , multivariate analysis , environmental health
Background Microvascular reconstruction is the standard of care in head and neck reconstruction, though its perioperative safety in an older population has been controversial due to safety concerns, warranting further investigation. Materials and methods An “older” (≥71 years) cohort undergoing reconstruction after mandibulectomy/glossectomy was compared to the remaining population in a National Surgical Quality Improvement Program (2008–2016) analysis. Cases required both a mandibulectomy/glossectomy and microvascular or local flap reconstruction (exclusion criteria: missing ages and simultaneous microvascular and local flap reconstruction). Demographics, comorbidities, and procedure types were analyzed on 985 patients (236 [24.4%] were ≥71). Outcomes were compared by reconstruction type. Regressions were performed calculating the impact of age on length of hospital stay (LOHS) and operative time. Results Ablative procedures were comparable, but older patients received local flaps at higher rates (22.5% vs. 9.6%; p  < .001). The older population had more comorbidities (higher ASA class [ p  < .001], diabetes [ p  < .001], and hypertension [ p  < .001]). After Bonferroni correction, univariate subgroup analyses of soft tissue and bone/composite microvascular flaps revealed similar outcomes (except increased medical complications in the older cohort undergoing a bone free flap [ p  = .002]). Controlling for a variety of factors, older age resulted in longer LOHS (B: 1.4 days; 95% CI: 0.1–2.8 days; p  = .035), but not operative time (B: −21.90 min; 95% CI: −52.76 to 8.96 min; p  = .164). Conclusion While increased age (≥70 years) was associated with a longer LOHS, complication rates were comparable. Although limited by the retrospective nature, evidence supports microvascular reconstruction in the elderly population with comparable outcomes.

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