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Composite reconstruction in advanced cancer of the mouth floor: Autogenous frozen‐thawed mandibular bone and free flaps
Author(s) -
Calabrese Luca,
Garusi Cristina,
Giugliano Gioacchino,
Ansarin Mohssen,
Bruschini Roberto,
Chiesa Fausto
Publication year - 2007
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.20301
Subject(s) - medicine , floor of mouth , dentistry , mandible (arthropod mouthpart) , orthodontics , surgery , oral cavity , botany , biology , genus
Mandibular symphyseal resection requires composite reconstructions, often with unsatisfactory morphofunctional results. Seven patients with advanced squamous cell carcinoma of the floor of the mouth underwent block resection with immediate reconstruction, using the removed mandible treated with liquid nitrogen and covered with a free forearm flap. In all cases, the resection was radical and no major postoperative complications occurred. Two patients died in 6 months for distant metastases and regional recurrence. In the other 5 patients, no local recurrence occurred at a mean follow‐up of 52 months (36–70). Immediate cosmetic and functional results were good. Of the 5 patients, 4 had late complications requiring further surgery. This technique of bone reimplantation produces no donor site morbidity, perfect immediate morphological result, and is of low cost. The free forearm flap is effective in sealing the oral cavity, though further clinical and experimental studies are necessary to reduce late local complications. © 2007 Wiley‐Liss, Inc. Microsurgery, 2007.