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Gamete microsurgery for assisted fertilization
Author(s) -
Sparks Amy E. T.
Publication year - 1995
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920160511
Subject(s) - microsurgery , intracytoplasmic sperm injection , human fertilization , medicine , spermatozoon , gamete , zona pellucida , dissection (medical) , in vitro fertilisation , andrology , oocyte , anatomy , embryo , surgery , biology , microbiology and biotechnology
Several methods of gamete microsurgery have been proposed to facilitate the union of the spermatozoon and oocyte in infertile couples. Partial zona dissection, subzonal sperm insertion, and intracytoplasmic sperm insertion are the three techniques currently being used for assisted fertilization in human in vitro fertilization laboratories. Fertilization and pregnancy rates after partial zona dissection and subzonal insertion have been variable and rather low. Recent reports of relatively high fertilization and pregnancy rates achieved after intracytoplasmic sperm insertion have rejuvenated interest in gamete microsurgery. Methods for each procedure are described. Studies which have attempted patient selection for gamete microsurgery are discussed. © 1995 Wiley‐Liss, Inc.