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The rat brachial plexus and its terminal branches: An experimental model for the study of peripheral nerve regeneration
Author(s) -
Bertelli Jayme Augusto,
Taleb Madgid,
Saadi Assia,
Mira JeanClaude,
PecotDechavassine Monique
Publication year - 1995
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920160207
Subject(s) - medicine , brachial plexus , musculocutaneous nerve , biceps , anatomy , peripheral nerve , epineurial repair , peripheral , plexus , muscle contracture , sciatic nerve , median nerve , surgery
Despite the introduction of microsurgical techniques into clinical practice, the results of surgical procedures involving the brachial plexus and peripheral nerves are still far from spectacular. We therefore studied the rat brachial plexus and its terminal branches in 203 rats. Detailed anatomic and morphologic analyses of the biceps brachii and musculocutaneous nerve, finger flexors, flexor carpi radialis, and the median nerve were performed. Various sources of conventional and vascularized nerve grafts were explored. After musculocutaneous nerve section or median nerve section, there were no articular contractures or automutilations, which constitutes an advantage for these experimental models over the sciatic nerve model. The brachial plexus and its terminal branches provide a good experimental model which can be used to assess the development and normal control of muscle function, examine the mechanisms underlying functional recovery, and test the effects of treatments to enhance recovery. © 1995 Wiley‐Liss, Inc.