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In vivo microscopy of a rat abdominal skin flap: A new model
Author(s) -
Whan Elizabeth B.,
Hurley John V.,
Morrison Wayne A.
Publication year - 1994
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920151114
Subject(s) - medicine , microcirculation , anatomy , microvessel , in vivo , plexus , blood supply , blood flow , intravital microscopy , microsurgery , vein , pathology , surgery , biology , radiology , immunohistochemistry , microbiology and biotechnology
This study describes a rat abdominal skin flap model of in vivo microscopy which provides a reliable, easy to perform system in which to examine the microcirculation of flaps. The island flap, which is based on the superficial inferior epigastric vessels caudally, and drained proximally by the lateral thoracic vein, can be mounted directly on a Perspex microscope stage. In vivo microscopy of the subdermal plexus of the flap allows detailed study of blood flow pattern, capillary flow, microvessel diameter, and margination of leucocytes, in a skin flap with versatile blood supply and innervation. © 1994 Wiley‐Liss, Inc.