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Cold (0°C) ischaemic tolerance of latissimus dorsi free flaps in rats: A macroscopic and morphological study
Author(s) -
Werker Paul M. N.,
Kon Moshe,
Green Colin J.,
Fryer Patricia R.,
Franken Ralph J. P. M.,
Overgoor Max L. E.
Publication year - 1994
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920150309
Subject(s) - medicine , surgery , anatomy
The purpose of this study was to define the cold (0°C) ischaemic tolerance (CIT) of the latissimus dorsi free flap in inbred rats. Flaps were isolated, stored at 0°C for periods of time ranging from 0 to 120 hr and then revascularised and reperfused for 14 days. Thereafter the CIT was assessed macroscopically, and by light microscopy. Electron microscopy was performed in flaps after 0 and 24 hr of reperfusion following a cold ischaemic interval ranging from 0 to 120 hr. From this preliminary study, it was concluded that the CIT was 48‐72 hr.