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Use of anticoagulants in replantation and elective microsurgery
Author(s) -
Siegel David B.
Publication year - 1991
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920120410
Subject(s) - medicine , microsurgery , replantation , antithrombotic , surgery , anastomosis , anticoagulant , anesthesia , intensive care medicine
Clinical and experimental data support the adjunctive use of anticoagulant medication following microvascular anastomosis. Local irrigating solutions, oral and intravenous anticoagulants, thrombolytic agents, plasma expanders, vasodilators, and antiplatelet medications are currently used in patients undergoing microsurgery, but for some time there has been considerable controversy over the agent or combination of agents that should be used and the optimal time when administration should begin and end. Over the past 15 years, however, experience with microsurgery for replantation and elective reconstruction has increased dramatically. With this greater experience and refined operative technique, the indications for varying anticoagulant regimens have changed so that it is now possible to make specific recommendations for antithrombotic therapy in traumatic and elective situations.