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Effects of venous hypertension on rabbit free flap survival
Author(s) -
Rooks Michael D.,
Gould John S.,
Masear Victoria,
Powell Jack H.,
Gould Sheryl
Publication year - 1991
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920120406
Subject(s) - medicine , free flap , venous pressure , blood flow , venous blood , surgery , venous return curve , blood pressure , venous hypertension , anesthesia , hemodynamics
A two‐stage project was developed to study the effect of increased venous pressure on blood flow and survival in microvascular free tissue transfers. A rabbit epigastric fasciocutaneous free flap model was used. The blood flow in the rabbit epigastric free flap is 1.07 ± 0.06 ml/min. The average venous pressure is 8.6 ± 1.7 cm water. A logarithmic relationship between blood flow and venous pressure was demonstrated, with a statistically significant decrease in blood flow to 20‐35% of the control values when the venous pressure rose above 28‐30 cm water. This study stands in support of the tolerance by free tissue transfers of pressures below this range. The results further show a positive correlation between increasing venous pressure and free flap failure.