Premium
Arterialization of the liver. III. influence of systemic and portal pressure gradients following heterotopic partial liver transplantation
Author(s) -
D'Silva Milbhor,
Pirenne Jacques,
Glassford Edmund,
Mayer David,
Bai Sang,
Gittes Ruben F.,
Lee Sun
Publication year - 1990
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920110217
Subject(s) - medicine , portal venous pressure , liver transplantation , portal hypertension , significant difference , orthotopic liver transplantation , transplantation , gastroenterology , surgery , cardiology , cirrhosis
An acute study was designed to compare blood pressures across a heterotopically transplanted partial liver graft using arterialized and nonarterialized models. Eight partial liver transplants (PLT) were done in each group, using Wistar rats. The data gathered from them are the basis for the results obtained herein. Whereas there was no significant difference (P > 0.01) in inflow, outflow, or the pressure difference across the PLT between nonarterialized and arterialized groups, host portal venous pressures were significantly higher (P < 0.01) in the arterialized group. A 1 mm arteriovenous fistula (AVF) was used to arterialize the PLTs in this study. It was proved that arterializing a PLT using a 1 mm AVF did not alter the pressure difference across the transplanted liver compared with the situation in the nonarterialized setting.