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Fibrinolytic activity following laser‐assisted vascular anastomosis
Author(s) -
Bailes Julian E.,
Quigley Matthew R.,
Kwaan Hau C.,
Cerullo Leonard J.,
Brown J. Thomas
Publication year - 1985
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920060307
Subject(s) - medicine , anastomosis , surgery
New technology has allowed tissue bonding to be feasible using carbon dioxide laser energy. Laser‐assisted vascular anastomosis (LAVA) has shown comparable patency results with standard suture anastomosis, but LAVA procedures produce thermally induced transmural structural alterations. To assess functional intimal recovery in LAVA versus sutured vessels, a fibrinolytic slide technique was utilized in 21 rats which had LAVA performed in one femoral artery while the opposite limb underwent a conventional microsuture anastomosis. Conventional anastomosis had persistent fibrinolytic activity while LAVA had return of fibrinolytic activity by 48 hours. Intimal fibrinolysis inhibition following LAVA is reversible and this technique does not lead to an increased incidence of thrombosis.