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Experimental foetal microsurgery as related to myelomeningocele
Author(s) -
Brunelli G.,
Brunelli F.
Publication year - 1984
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920050106
Subject(s) - medicine , microsurgery , adhesion , surgery , hydrocephalus , spinal cord , scar tissue , fetal surgery , anatomy , fetus , pregnancy , in utero , chemistry , organic chemistry , psychiatry , biology , genetics
Abstract To study the capacity of embryono‐foetal tissue to regenerate without scar formation, experimental intrauterine surgery has been carried out in rabbits. This study has been performed with regard to the possibility of using intrauterine microsurgery to correct myelomeningocele in humans to avoid scar adhesion between the medulla and the growing vertebral bones and subsequent hydrocephalus. Lesions were produced in the spinal cord of rabbit foetuses, and observation after birth showed repair without scar formation. Further research is in progress to confirm these findings and to adapt this procedure to the clinical situation.