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Comparison of efficacy of thrombolysin, streptokinase, and urokinase in a femoral vein clot model in rats
Author(s) -
Cooley Brian C.,
Jones Mark M.,
Dellon A. Lee
Publication year - 1983
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920040105
Subject(s) - streptokinase , urokinase , medicine , femoral vein , vein , thrombolysis , surgery , cardiology , myocardial infarction
A venous clot model in rats was used to compare the ability of locally infused thrombolytic agents to lyse clots. Urokinase and a combination of streptokinase and human plasminogen (Thrombolysin) proved to be equally effective in lysing clots. In comparison, streptokinase alone was not as effective a thrombolytic agent in this model.