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The effect of temperature on tolerance to ischemia in experimental free flaps
Author(s) -
Cooley Brian C.,
Hansen Frederick C.,
Dellon A. Lee
Publication year - 1981
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1920030105
Subject(s) - medicine , ischemia , groin , surgery , anesthesia , cardiology
Abstract Extended groin flaps in rats were used to explore the relationship of time and temperature of ischemic storage to the ultimate survival of free flaps. The maximum period of ischemia with 100% survival was found to be six hours for storage at a normothermic range (20‐ 25‐ C) and 48 hours for storage at a hypothermic range (0‐ 5 C). This study confirms the findings of others that cooling of tissue increases the interval of ischemic storage in which composite tissue can withstand and still survive.