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A new vascularized adrenal transplantation model in the rat
Author(s) -
Liu Dingyi,
Qi Shijie,
Xu Dasheng,
Zhu Shengyun,
Chen Huifang
Publication year - 2001
Publication title -
microsurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.031
H-Index - 63
eISSN - 1098-2752
pISSN - 0738-1085
DOI - 10.1002/micr.1022
Subject(s) - medicine , anastomosis , inferior vena cava , microsurgery , transplantation , aorta , surgery , rat model , vein , artery , anatomy
Abstract A new microsurgical model of adrenal transplantation in the rat is described. An adrenal graft with its vascular supply, adrenal artery and vein, and the attachment of a segment of aorta and inferior vena cava (IVC) was transplanted to a recipient rat with end‐to‐side anastomoses between the donor IVC segment and the recipient IVC and between the donor aortic segment and the recipient aorta using 10‐0 nylon sutures. Using this model, different groups of recipient rats received iso‐ or allograft with or without immunosuppressive treatment were tested. This model provides a reliable and useful tool for research on endocrinology. © 2001 Wiley‐Liss, Inc. MICROSURGERY 21:124–126 2001