Open AccessGenetics and genomics etiology of nonsyndromic orofacial clefts
Author(s) -
Adeyemo Wasiu L.,
Butali Azeez
Publication year - 2017
Publication title -
molecular genetics and genomic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.765
H-Index - 29
ISSN - 2324-9269
DOI - 10.1002/mgg3.272
Subject(s) - etiology , genomics , bioinformatics , genetics , computational biology , biology , medicine , genome , gene , pathology
Orofacial clefts ( OFC ) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools.