Open AccessSurvey of Ehlers‒Danlos Patients’ ophthalmic surgery experiences
Author(s) -
Louie Anita,
Meyerle Catherine,
Francomano Clair,
Srikumaran Divya,
Merali Farhan,
Doyle Jefferson J.,
Bower Kraig,
Bloom Lara,
Boland Michael V.,
Mahoney Nicholas,
Daoud Yassine,
Singman Eric L.
Publication year - 2020
Publication title -
molecular genetics and genomic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.765
H-Index - 29
ISSN - 2324-9269
DOI - 10.1002/mgg3.1155
Subject(s) - medicine , ophthalmic surgery , refractive surgery , cataract surgery , strabismus surgery , ehlers–danlos syndrome , ocular surgery , ophthalmology , surgery , glaucoma , glaucoma surgery , strabismus , cornea , laser surgery , laser , physics , optics
Background Ehlers‒Danlos Syndrome (EDS) is a rare disease affecting approximately 1 in 5,000 people. Although ophthalmic conditions associated with EDS have been described, little data exist concerning ophthalmic surgical outcomes experienced by EDS patients. Methods Patients with EDS were surveyed via the EDS Society and asked about their ophthalmic surgical experiences including procedure, complications, and the timing with respect to receiving the EDS diagnosis. Complications were confirmed as such by subspecialists. Results Of 579 respondents, 467 reported confirmed EDS, and 112 of those had an ophthalmic procedure, including refractive surgery, cataract/lens surgery, retinal surgery, strabismus surgery, oculoplastic surgery, corneal surgery, and laser surgery for glaucoma. The rate of confirmed complications was: 23%‐refractive, 33%‐lens/cataract, 33%‐retina, 59%‐strabismus, 23%‐ oculoplastics, 0%‐cornea, and 25%‐glaucoma laser. In addition, 76% of patients underwent surgery prior to the EDS diagnosis. Conclusions Patients with EDS may have elevated risk of postoperative ophthalmic surgical complications. It would seem reasonable to systemically and prospectively explore how patients with EDS respond to ophthalmic surgery. Furthermore, it would seem circumspect to ask surgical candidates patients about whether they carry a diagnosis of EDS or have signs and symptoms of EDS prior to surgery.