Open AccessRETRACTED: Population genetic data from 23 autosomal STR loci of Huaxia Platinum system in the Jining Han population
Author(s) -
Dang Zhen,
Liu Qi,
Zhang Guoan,
Li Shuyue,
Wang Dan,
Pang Qianqian,
Yang Da,
Li Changzheng,
Cui Wen,
Wang Yequan
Publication year - 2020
Publication title -
molecular genetics and genomic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.765
H-Index - 29
ISSN - 2324-9269
DOI - 10.1002/mgg3.1142
Subject(s) - kazakh , genetics , population , allele , biology , han chinese , microsatellite , allele frequency , genetic relationship , traditional medicine , single nucleotide polymorphism , gene , genotype , genetic diversity , demography , medicine , philosophy , linguistics , sociology
Background Genetic polymorphisms at 23 short tandem repeat (STR) loci were investigated in 1,215 Jining Han individuals from Jining city, Shandong province, eastern China. Methods We used population genetic data of 23 autosomal STR loci included in the Huaxia Platinum system to evaluate 1,215 unrelated Chinese Han individuals in the Jining Han population. Allele frequencies and forensic parameters of the STR loci were determined and genetic relationships among the Jining Han and other Chinese populations were evaluated. Results In total, we observed 321 alleles, with frequencies ranging from 0.00041 to 0.52222. The combined discrimination power and probability of excluding paternity were 0.19 and 0.62, respectively. No deviations from HWE were observed at any loci. Population comparisons showed that the Xinjiang groups (Uyghur and Kazakh) and the Mongolian and Tibetan groups were isolated, while the Jining Han population clustered together with other populations, except the Guizhou Han population. Conclusion This study demonstrated that 23 autosomal STR loci included in the Huaxia Platinum system are highly polymorphic and suitable for personal forensic identification and paternity testing in this population.