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Phytochemistry and cardiovascular protective effects of Huang‐Qi (Astragali Radix)
Author(s) -
Su Huifei,
Shaker Sharpkate,
Kuang Yi,
Zhang Meng,
Ye Min,
Qiao Xue
Publication year - 2021
Publication title -
medicinal research reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.868
H-Index - 130
eISSN - 1098-1128
pISSN - 0198-6325
DOI - 10.1002/med.21785
Subject(s) - astragalus , traditional medicine , radix (gastropod) , phytochemistry , traditional chinese medicine , pharmacognosy , pharmacology , medicine , biology , biological activity , botany , biochemistry , in vitro , alternative medicine , pathology
Huang‐Qi (Astragali Radix) is an herbal tonic widely used in China and many other countries. It is derived from the roots of Astragalus membranaceus and A. membranaceus var. mongholicus and shows potent cardiovascular protective effects. In this article, we comprehensively reviewed 189 small molecules isolated from the two Astragalus species and discussed the interspecies chemical differences. Moreover, we summarized the pharmacological activities and mechanisms of action of Huang‐Qi and its major bioactive compounds for the treatment of cardiovascular diseases. This review covers 171 references published between February 1983 and March 2020.