z-logo
open-access-imgOpen Access
Biodegradable 3D porous zinc alloy scaffold for bone fracture fixation devices
Author(s) -
Bobby Kannan M,
Chappell Jonathon,
Khakbaz Hadis,
Taherishargh Mehdi,
Fiedler Thomas
Publication year - 2020
Publication title -
medical devices & sensors
Language(s) - English
Resource type - Journals
ISSN - 2573-802X
DOI - 10.1002/mds3.10108
Subject(s) - alloy , materials science , porosity , simulated body fluid , zinc , chemical engineering , casting , composite material , metallurgy , scanning electron microscope , engineering
In this study, a three‐dimensional (3D) porous zinc alloy (Zn‐Al 4 ) scaffold was produced using counter‐gravity infiltration casting method and its in vitro degradation behaviour was evaluated using an electrochemical technique in simulated body fluid (SBF) for potential applications in bone fracture fixation devices. The porous zinc alloy exhibited porosity of ~60% with interconnected pores, and the pore size was 1–2 mm. The in vitro potentiodynamic polarization results showed that the degradation rate of the porous zinc alloy was 0.16 mm/year, which is ~15% higher than that of the non‐porous pure zinc metal (0.14 mm/year). Highly biocompatible calcium phosphate (CaP) was electrochemically deposited on the porous zinc alloy and its in vitro degradation behaviour was also studied. The micrographs of the CaP deposited porous zinc alloy revealed uniformly coverage of CaP particles on the outer surface of the alloy and partial deposition on the inside of the pores. The morphology of the deposited CaP particles was predominantly spherical‐shaped, but flake‐like particles were also evident on the inside of the pores. Interestingly, the degradation rate of the CaP deposited porous zinc alloy (0.5 mm/year) was three times higher than that of the porous zinc alloy. It can be hypothesized that the restricted SBF flow through the partially blocked pores by the CaP particles have locally raised the pH inside the pores and thus increased the degradation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here