Open AccessMADVent: A low‐cost ventilator for patients with COVID‐19
Author(s) -
Vasan Aditya,
Weekes Reiley,
Connacher William,
Sieker Jeremy,
Stambaugh Mark,
Suresh Preetham,
Lee Daniel E.,
Mazzei William,
Schlaepfer Eric,
Vallejos Theodore,
Petersen Johan,
Merritt Sidney,
Petersen Lonnie,
Friend James
Publication year - 2020
Publication title -
medical devices & sensors
Language(s) - English
Resource type - Journals
ISSN - 2573-802X
DOI - 10.1002/mds3.10106
Subject(s) - covid-19 , economic shortage , authorization , acute respiratory distress , medicine , ards , mechanical ventilator , medical emergency , intensive care medicine , risk analysis (engineering) , computer science , computer security , mechanical ventilation , anesthesia , lung , linguistics , philosophy , disease , pathology , government (linguistics) , infectious disease (medical specialty)
The COVID‐19 pandemic has produced critical shortages of ventilators worldwide. There is an unmet need for rapidly deployable, emergency‐use ventilators with sufficient functionality to manage COVID‐19 patients with severe acute respiratory distress syndrome. Here, we show the development and validation of a simple, portable and low‐cost ventilator that may be rapidly manufactured with minimal susceptibility to supply chain disruptions. This single‐mode continuous, mandatory, closed‐loop, pressure‐controlled, time‐terminated emergency ventilator offers robust safety and functionality absent in existing solutions to the ventilator shortage. Validated using certified test lungs over a wide range of compliances, pressures, volumes and resistances to meet U.S. Food and Drug Administration standards of safety and efficacy, an Emergency Use Authorization is in review for this system. This emergency ventilator could eliminate controversial ventilator rationing or splitting to serve multiple patients. All design and validation information is provided to facilitate ventilator production even in resource‐limited settings.