Open AccessSelf‐powered polymer–metal oxide hybrid solar cell for non‐enzymatic potentiometric sensing of bilirubin
Author(s) -
Manikandan Palinci Nagarajan,
Imran Habibulla,
Dharuman Venkataraman
Publication year - 2019
Publication title -
medical devices & sensors
Language(s) - English
Resource type - Journals
ISSN - 2573-802X
DOI - 10.1002/mds3.10031
Subject(s) - bilirubin oxidase , chemistry , potentiometric titration , detection limit , polyvinyl alcohol , materials science , electrode , chromatography , organic chemistry
Abstract Biofuel cell and enzyme‐based self‐powered sensors (SPS) have been reported for various metabolite sensing. However, it is essential to eliminate enzymes to reduce the cost and long‐term stability of the SPS. Here, we developed polymer (polyaniline–polyvinyl alcohol) and metal oxide (aluminium‐doped zinc oxide) hybrid solar cell self‐powered potentiometric sensor for bilirubin (BR) quantification accurately in blood. The hybrid solar device showed an open circuit potential (OCP) of 0.427 V and increases to 0.8 V upon visible light irradiation and interaction with bilirubin. The sensor shows dynamic range from 3 µg/dl to 87 mg/dl (0.05 µM–1.5 mM) with r 2 0.9981 with detection limit of 1.2 ± 0.06 µg/dl. Data reading was achieved by connecting a simple multimeter without using any other active electronic components. Blood bilirubin from the jaundice patients is quantified and compared with the biochemical assay.