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A new tremor mutant in the pietrain pig: An animal model of orthostatic tremor? Clinical and neurophysiological observations
Author(s) -
Wissel Jörg,
Harlizuis Barbara,
Richter Angelica,
Löscher Wolfgang,
Schelosky Ludwig,
Scholz Udo,
Poewe Werner
Publication year - 1997
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870120519
Subject(s) - physical medicine and rehabilitation , orthostatic vital signs , electromyography , neurophysiology , medicine , movement disorders , essential tremor , psychology , neuroscience , disease , blood pressure
A new tremor mutant, the “Campus syndrome” was studied in a breed of Pietrain pigs. Affected pigs showed a coarse tremor of the extremities when standing and walking, so they tended to remain recumbent, during which the tremor was suppressed. Needle electromyographic recordings of the semitendinosus muscle plus accelerometry revealed a high‐amplitude 14‐ to 15‐Hz tremor pattern activated specifically upon standing but maintained during walking. The observed syndrome thus bears similarities to the human condition of orthostatic tremor and might serve as an animal model for this as yet poorly understood disorder.