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A family with hereditary juvenile dystonia‐parkinsonism
Author(s) -
Ishikawa Atsushi,
Miyatake Tadashi
Publication year - 1995
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870100413
Subject(s) - dystonia , parkinsonism , levodopa , dyskinesia , medicine , myoclonus , neurological disorder , movement disorders , torticollis , spasmodic torticollis , family history , physical medicine and rehabilitation , psychology , pediatrics , central nervous system disease , surgery , anesthesia , parkinson's disease , psychiatry , disease
We report a family with autosomal dominant type hereditary juvenile dystonia‐parkinsonism in which eight members in three generations exhibited parkinsonism, sleep benefit, marked efficacy of levodopa, wearing‐off phenomenon, and dopa‐induced choreic dyskinesia. However, one case showed mainly dystonic movement that worsened after administration of levodopa. The patients in this family showed neck dystonia, such as torticollis and retrocollis, in addition to foot dystonia and other dystonic movement, such as frequently lifting the thigh. From the family history and clinical findings, these patients are considered to have a specific form of hereditary dystonia‐parkinsonism.