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Familial levodopa‐responsive parkinsonian‐pyramidal syndrome
Author(s) -
Nisipeanu P.,
Kuritzky A.,
Korczyn A. D.
Publication year - 1994
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870090614
Subject(s) - levodopa , degenerative disease , central nervous system disease , medicine , pediatrics , psychology , parkinson's disease , disease
We present four patients—two pairs of siblings—followed for many years, with pyramidal and parkinsonian features, who responded consistently to levodopa therapy. The patients belong to two unrelated consanguineous families, suggesting that this condition is genetically determined and recessively inherited.