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Hemiballism and chorea in a patient with parkinsonism due to a multisystem degeneration
Author(s) -
Steiger M. J.,
Pires M.,
Scaravilli F.,
Quinn N. P.,
Marsden C. D.
Publication year - 1992
Publication title -
movement disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.352
H-Index - 198
eISSN - 1531-8257
pISSN - 0885-3185
DOI - 10.1002/mds.870070115
Subject(s) - chorea , parkinsonism , levodopa , degeneration (medical) , medicine , basal ganglia , dopaminergic , movement disorders , parkinson's disease , degenerative disease , pathological , central nervous system disease , disease , surgery , anesthesia , pathology , dopamine , central nervous system
Abstract Dyskinesias associated with dopaminergic treatment in idiopathic Parkinson's disease (PD) can be indistinguishable from those arising spontaneously in other conditions involving degeneration of, or damage to, the basal ganglia. However, those due to levodopa treatment of PD disappear on cessation of therapy. We report a patient with a clinical diagnosis of PD who, on levodopa treatment, developed hemiballism and chorea that were originally thought to be drug induced. However, the dyskinesias persisted despite stopping levodopa. Postmortem analysis showed a multisystem degeneration.